Possible conformations of double-helical polynucleotides containing incorrect base pairs
نویسندگان
چکیده
منابع مشابه
The stability of helical polynucleotides: base contributions.
Estimates have been made of the main contributions of the heterocyclic bases of DNA to the free energies of the two configurations in solution, the two-stranded helix and the single-strand random coil. The magnitude and directions of the dipole moments of the adenine, thymine, guanine and cytosine base groups have been calculated by a semi-empirical molecular orbital treatment. Dipole-dipole, d...
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In this paper, two double helical dinuclear copper(II) complexes of bis-N,O-bidentate Schiff base ligands bis(3-methoxy-N-salicylidene-4,4'-diaminodiphenyl)sulfone (L1) and bis(5-bromo-N-salicylidene-4,4'-diaminodiphenyl)sulfone (L2) were prepared and characterized by elemental analyses (CHN), as well as thermal analysis. Elemental analyses (CHN) suggested that the reaction between ligands and ...
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8 C. C. Stock, "Experimental Cancer Chemotherapy," in Advances in Cancer Research, ed. J. P. Greenstein and A. Haddow, 2 (New York: Academic Press, Inc., 1954), 425-492. 9 D. M. Shapiro and A. Gellhorn, "Combinations of Chemical Compounds in Experimental Cancer Therapy," Cancer Research, 11, 35-41, 1951; D. M. Shapiro, "Combination Chemotherapy with 8-Azaguanine and Sex Hormones on a Mouse Mamm...
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Mismatched base pairs, such as different conformations of the G.A mispair, cause only minor structural changes in the host DNA molecule, thereby making mispair recognition an arduous task. Electron transport in DNA that depends strongly on the hopping transfer integrals between the nearest base pairs, which in turn are affected by the presence of a mispair, might be an attractive approach in th...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1983
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/11.15.5205